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微生物学、生物化学与分子生物学

孟祥锋

教授
硕士生导师
0532-58632405
个人简介 科研项目 学术论文 其他介绍

教育背景:

博士  2010.10-2014.12  荷兰格罗宁根大学  专业:微生物生理

硕士  2007.09-2010.07  bet365 코리아  专业:微生物

学士  2003.09-2007.07  bet365 코리아  专业:生命科学基地


工作经历:

2023.09-现在  bet365 코리아bet365 코리아  教授

2016.12-2023.09  bet365 코리아bet365 코리아  副研究员

2015.01-2016.12  荷兰格罗宁根大学  博士后


研究方向:

丝状真菌蛋白分泌机制研究

丝状真菌天然产物研究

碳水化合物作用酶的挖掘及应用

主要项目:

1. 国家自然科学基金面上项目,主持

2. 国家重点研发计划子课题,主持

3. 国家自然科学青年基金,主持

4. 山东省自然科学基金博士基金,主持

5. bet365 코리아未来学者计划,主持

6. 中国博士后科学基金面上项目,主持

7. bet365 코리아基本科研业务经费,主持

代表性论文:

1. Li Z, Waghmare P, Dijkhuizen L,Meng X*, Liu W (2024) Research advances on the consolidated bioprocessing of lignocellulosic biomass. Engineering Microbiology, 4:100139

2. Fang Y, Dong M, van Leeuwen S, Dijkhuizen L,Meng X*, Liu W(2023) Biochemical characterization of glycoside hydrolase family 31 a-glucosidases fromMyceliophthora thermophilafor a-glucooligosaccharide synthesis. Int J Biol Macromol, 252:126452

3. Wang Z, Yang R, Lv W, Zhang W,Meng X*, Liu W (2022) Functional characterization of sugar transporter CRT1 reveals differential roles of its C-terminal region in sugar transport and cellulase induction inTrichoderma reeseiMicrobiol Spectr, 10(4):e0087222.

4. Rawat PS, Li Y, Zhang W,Meng X*, Liu W (2022)Hungatella hathewayi, an efficient glycosaminoglycan-degrading firmicutes from human gut and its chondroitin ABC exolyase with high activity and broad substrate specificity. Appl Environ Microbiol, 88(22):e0154622.

5. Meng X, Li X, Pijning T, Wang X, van Leeuwen SS, Dijkhuizen L, Chen G*, Liu W* (2022) Characterization of the (engineered) branching sucrase GtfZ-CD2 fromApilactobacillus kunkeeifor efficient glucosylation of benzenediol compounds. Appl Environ Microbiol, 88(16):e0103122.

6. Meng X, Fang Y, Ding M, Zhang Y, Jia K, Li Z, Collemare J*, Liu W* (2021) Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity. Biotechnol Adv, 54:107866.

7. Liu L, Xu M, Cao Y, Wang H, Shao J, Xu M, Zhang Y, Wang Y, Zhang W,Meng X*, Liu W (2020) Biochemical characterization of xylanases fromStreptomyces sp.B6 and their application in the xylooligosaccharide production from viscose fiber production waste. J Agric Food Chem, 68(10):3184-3194.

8. Meng, X., Liu, H., Xu, W., Zhang, W., Wang, Z., & Liu, W*. (2020). Metabolic engineeringSaccharomyces cerevisiaefor de novo production of the sesquiterpenoid (+)-nootkatone. Microb Cell Fact, 19(1), 21.

9. Wang L, Zheng F, Zhang W, Zhong Y, Chen G,Meng X*,Liu W (2018) A copper-controlled RNA interference system for reversible silencing of target genes inTrichoderma reeseiBiotechnol Biofuels, 11: 33.

10. Meng X, Gangoiti J, de Kok N, van Leeuwen SS, Pijning T, Dijkhuizen L (2018) Biochemical characterization of two GH70 family 4,6-α-glucanotransferases with distinct product specificity fromLactobacillus aviariussubsp.aviariusDSM 20655. Food Chem, 253:236-246.

授权专利:

1. 一株高产岩藻糖基乳糖的酿酒酵母工程菌株及其应用,专利号:ZL202010187309.1,第一位

2. 一株优化的高产岩藻糖基乳糖的酿酒酵母菌株及其应用,专利号:ZL202010187362.9,第二位

3. 一种耐碱耐热的木聚糖酶及其应用,专利号:ZL201911194651.8,第二位